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Guasdualito | |
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  Guasdualito .svg) Guasdualito | |
| Coordinates: 07°14′48″N 70°43′45″W / 7.24667°N 70.72917°W | |
| Country |  Venezuela |
| State | Apure |
| Municipality | Páez Municipality |
| Founded | 1770/1 |
| Elevation | 125 m (410 ft) |
| Population | |
| • Total | 105,000 |
| • Demonym | Guasdualiteño/a |
| Time zone | UTC−4 (VET) |
| Postal code | 5063 |
| Area code | 0278 |
| Climate | Aw |
Guasdualito is a city and episcopal see in the landlocked Apure State, in southern Venezuela.