The Guaycura (Waicura, Waikuri, Guaycuri) were a native people of Baja California Sur, Mexico, occupying an area extending south from near Loreto to Todos Santos. They contested the area around La Paz with the Pericú. The Guaycura were nomadic hunter-gatherers. They are distinguished by a language unrelated to any other Native American language, indicating in the opinion of some linguists that their ancestry in Baja California dates back thousands of years.
The Society of Jesus (Jesuits) of the Catholic Church established Christian missions in their territory in the 18th century. The Guaycura may have numbered 5,000 at the time of Spanish contact, but their numbers quickly declined, mostly due to European diseases.[1] They became extinct as a culture by about 1800, the survivors being absorbed into the mestizo society of Mexico.