Gymnema sylvestre

Gymnema sylvestre
Gymnema sylvestre, at Eastern Ghats, India
Scientific classification Edit this classification
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Asterids
Order: Gentianales
Family: Apocynaceae
Genus: Gymnema
Species:
G. sylvestre
Binomial name
Gymnema sylvestre

Gymnema sylvestre[1] is a perennial woody vine native to Asia (including the Arabian Peninsula), Africa and Australia. It has been used in Ayurvedic medicine. Common names include gymnema,[2] Australian cowplant, and Periploca of the woods, and the Hindi term gurmar, which means "sugar destroyer".[3][4][5]

The leaves and extracts contain gymnemic acids, the major bioactive constituents that interact with taste receptors on the tongue to temporarily suppress the taste of sweetness.[6][7][8][9][10]

  1. ^ "Integrated Taxonomic Information System". www.itis.gov. Retrieved 2018-02-01.
  2. ^ Duke JA, ed. (2002). Handbook of medicinal herbs (2nd ed.). CRC Press. p. 855. ISBN 978-0-8493-1284-7.
  3. ^ Quattrocchi U (1999-11-23). CRC World Dictionary of Plant Names: Common Names, Scientific Names, Eponyms, Synonyms, and Etymology. Taylor & Francis US. ISBN 978-0849326769.
  4. ^ Tiwari P, Mishra BN, Sangwan NS (2014). "Phytochemical and pharmacological properties of Gymnema sylvestre: an important medicinal plant". BioMed Research International. 2014: 830285. doi:10.1155/2014/830285. PMC 3912882. PMID 24511547.
  5. ^ Ulbricht C, Abrams TR, Basch E, Davies-Heerema T, Foppa I, Hammerness P, Rusie E, Tanguay-Colucci S, Taylor S, Ulbricht C, Varghese M, Weissner W, Woods J (2011). "An evidence-based systematic review of gymnema (Gymnema sylvestre R. Br.) by the Natural Standard Research Collaboration". Journal of Dietary Supplements. 8 (3): 311–30. doi:10.3109/19390211.2011.597977. PMID 22432729. S2CID 29228955.
  6. ^ Kurihara Y (1969). "Antisweet activity of gymnemic acid A1 and its derivatives". Life Sciences. 8 (9): 537–43. doi:10.1016/0024-3205(69)90449-4. PMID 5791706.
  7. ^ Gent JF, Hettinger TP, Frank ME, Marks LE (1999). "Taste confusions following gymnemic acid rinse". Chemical Senses. 24 (4): 393–403. doi:10.1093/chemse/24.4.393. PMID 10480675.
  8. ^ Sanematsu K, Kusakabe Y, Shigemura N, Hirokawa T, Nakamura S, Imoto T, Ninomiya Y (September 2014). "Molecular mechanisms for sweet-suppressing effect of gymnemic acids". The Journal of Biological Chemistry. 289 (37): 25711–20. doi:10.1074/jbc.M114.560409. PMC 4162174. PMID 25056955.
  9. ^ Gardner Z, McGuffin M (2013). American Herbal Products Association's Botanical Safety Handbook, Second Edition. CRC Press. ISBN 978-1466516946.
  10. ^ Brala PM, Hagen RL (January 1983). "Effects of sweetness perception and caloric value of a preload on short term intake". Physiology & Behavior. 30 (1): 1–9. doi:10.1016/0031-9384(83)90030-6. PMID 6836034. S2CID 21639511.