HK3

HK3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesHK3, HKIII, HXK3, hexokinase 3
External IDsOMIM: 142570; MGI: 2670962; HomoloGene: 55633; GeneCards: HK3; OMA:HK3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002115

NM_001033245
NM_001206390
NM_001206391
NM_001206392

RefSeq (protein)

NP_002106

NP_001028417
NP_001193319
NP_001193320
NP_001193321

Location (UCSC)Chr 5: 176.88 – 176.9 MbChr 13: 55.15 – 55.17 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Hexokinase 3 also known as HK3 is an enzyme which in humans is encoded by the HK3 gene on chromosome 5.[5][6] Hexokinases phosphorylate glucose to produce glucose-6-phosphate (G6P), the first step in most glucose metabolism pathways. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate. [provided by RefSeq, Apr 2009][7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000160883Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025877Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Furuta H, Nishi S, Le Beau MM, Fernald AA, Yano H, Bell GI (August 1996). "Sequence of human hexokinase III cDNA and assignment of the human hexokinase III gene (HK3) to chromosome band 5q35.2 by fluorescence in situ hybridization". Genomics. 36 (1): 206–9. doi:10.1006/geno.1996.0448. PMID 8812439.
  6. ^ Colosimo A, Calabrese G, Gennarelli M, Ruzzo AM, Sangiuolo F, Magnani M, Palka G, Novelli G, Dallapiccola B (1996). "Assignment of the hexokinase type 3 gene (HK3) to human chromosome band 5q35.3 by somatic cell hybrids and in situ hybridization". Cytogenetics and Cell Genetics. 74 (3): 187–8. doi:10.1159/000134409. PMID 8941369.
  7. ^ "Entrez Gene: HK3 hexokinase 3 (white cell)".