HLA-A29

HLA-A29
HLA-A29
(MHC Class I, A cell surface antigen)
	HLA-A29
About
Protein	transmembrane receptor/ligand
Structure	αβ heterodimer
Subunits	HLA-A*29--, β2-microglobulin
Older names	A19
Subtypes
Subtype
Subtype	allele
A29.1	*2901
A29.2	*2902
{{{cNick3}}}	*29{{{cAllele3}}}
{{{cNick4}}}	*29{{{cAllele4}}}
	Alleles link-out to IMGT/HLA database at EBI

HLA-A29 (A29) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α²⁹ subset of HLA-A α-chains. For A29, the alpha "A" chain are encoded by the HLA-A*29 allele group and the β-chain are encoded by B2M locus.^[1] This group currently is dominated by A*2902. A29 and A*29 are almost synonymous in meaning. A29 is a split antigen of the broad antigen serotype A19. A29 is a sister serotype of A30, A31, A32, A33, and A74.

A29 is more common in Western Africa and Southwestern Europe.

Serotype

A29 recognition of some HLA A*29 gene products^[2]
A*29	A29	Sample
allele	%	size (N)
*2901	96	119
*2902	99	1148

^ Arce-Gomez B, Jones EA, Barnstable CJ, Solomon E, Bodmer WF (February 1978). "The genetic control of HLA-A and B antigens in somatic cell hybrids: requirement for beta2 microglobulin". Tissue Antigens. 11 (2): 96–112. doi:10.1111/j.1399-0039.1978.tb01233.x. PMID 77067.
^ Allele Query Form IMGT/HLA - European Bioinformatics Institute

[pmid77067-1] Arce-Gomez B, Jones EA, Barnstable CJ, Solomon E, Bodmer WF (February 1978). "The genetic control of HLA-A and B antigens in somatic cell hybrids: requirement for beta2 microglobulin". Tissue Antigens. 11 (2): 96–112. doi:10.1111/j.1399-0039.1978.tb01233.x. PMID 77067.

[2] Allele Query Form IMGT/HLA - European Bioinformatics Institute

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