HLA-A30

HLA-A30
(MHC Class I, A cell surface antigen)
HLA-A30
About
Proteintransmembrane receptor/ligand
Structureαβ heterodimer
SubunitsHLA-A*30--, β2-microglobulin
Older namesA19
Subtypes
Subtype
allele
Available structures
A30.3 *3001
A30.2 *3002
{{{cNick3}}} *30{{{cAllele3}}}
{{{cNick4}}} *30{{{cAllele4}}}
Rare alleles
Subtype
allele
Available structures
A30.4 *3004
{{{rnick2}}} *30{{{rallele2}}}
{{{rnick3}}} *30{{{rallele3}}}
Alleles link-out to IMGT/HLA database at EBI

HLA-A30 (A30) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α30 subset of HLA-A α-chains. For A30, the alpha "A" chain are encoded by the HLA-A*30 allele group and the β-chain are encoded by B2M locus.[1] A30 and A*30 are almost synonymous in meaning. A30 is a split antigen of the broad antigen serotype A19. A30 is a sister serotype of A29A31A32A33, and A74.


Serotype

[edit]
A30 recognition of some HLA A*30 gene products[2]
A*30 A30 A19 A31 Sample
allele % % % size (N)
*3001 89 1 3 3517
*3002 93 1 2 2124
*3004 94 0 0   85



  1. ^ Arce-Gomez B, Jones EA, Barnstable CJ, Solomon E, Bodmer WF (February 1978). "The genetic control of HLA-A and B antigens in somatic cell hybrids: requirement for beta2 microglobulin". Tissue Antigens. 11 (2): 96–112. doi:10.1111/j.1399-0039.1978.tb01233.x. PMID 77067.
  2. ^ Allele Query Form IMGT/HLA - European Bioinformatics Institute