HLA-A31 | ||||||||||||||||
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(MHC Class I, A cell surface antigen) | ||||||||||||||||
About | ||||||||||||||||
Protein | transmembrane receptor/ligand | |||||||||||||||
Structure | αβ heterodimer | |||||||||||||||
Subunits | HLA-A*3101, β2-microglobulin | |||||||||||||||
Older names | A19 | |||||||||||||||
Subtypes | ||||||||||||||||
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Rare alleles | ||||||||||||||||
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Alleles link-out to IMGT/HLA database at EBI |
HLA-A31 (A31) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α31 subset of HLA-A α-chains. For A31, the alpha "A" chain are encoded by the HLA-A*31 allele group and the β-chain are encoded by B2M locus.[1] This group currently is dominated by A*3101. A31 and A*31 are almost synonymous in meaning. A31 is a split antigen of the broad antigen serotype A19. A31 is a sister serotype of A29, A30, A32, A33, and A74.
A31 is more common in South and Central America.
A*31 | A31 | A19 | A30 | Sample |
allele | % | % | % | size (N) |
*3101 | 90 | 1 | 3 | 3517 |
*3102 | 100 | 0 | 0 | 11 |
There is substantive false reaction of A30 with A*3101, otherwise serological identification is good.