HLA-A32

HLA-A32
(MHC Class I, A cell surface antigen)
HLA-A32
About
Protein	transmembrane receptor/ligand
Structure	αβ heterodimer
Subunits	HLA-A*3201, β2-microglobulin
Older names	"A19"
Subtypes
Subtype allele Available structures A19 *3201 {{{cNick2}}} *32{{{cAllele2}}} {{{cNick3}}} *32{{{cAllele3}}} {{{cNick4}}} *32{{{cAllele4}}}
Alleles link-out to IMGT/HLA database at EBI

HLA-A32 (A32) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α³² subset of HLA-A α-chains. For A32, the alpha "A" chain are encoded by the HLA-A*32 allele group and the β-chain are encoded by B2M locus.^[1] This group currently is dominated by A*3201. A32 and A*32 are almost synonymous in meaning. A32 is a split antigen of the broad antigen serotype A19. A32 is a sister serotype of A29, A30, A31, A33, and A74.

A32 Serotyping efficiency for the predominant allele is good. There are 16 known alleles that result in 15 isoforms of HLA-A32. One isoform may be poorly expressed.^[3].