This article may be too technical for most readers to understand.(May 2017) |
HLA-A36 | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
(MHC Class I, A cell surface antigen) | ||||||||||||||||
About | ||||||||||||||||
Protein | transmembrane receptor/ligand | |||||||||||||||
Structure | αβ heterodimer | |||||||||||||||
Subunits | HLA-A*3601, β2-microglobulin | |||||||||||||||
Subtypes | ||||||||||||||||
| ||||||||||||||||
Alleles link-out to IMGT/HLA database at EBI |
HLA-A36 (A36) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α36 subset of HLA-A α-chains. For A36, the alpha "A" chain are encoded by the HLA-A*36 allele group and the β-chain are encoded by B2M locus.[1] This group currently is dominated by A*3601. A36 and A*36 are almost synonymous in meaning.
A36 is more common in Africa (North and East) and Central Asia. A36 is rare HLA-A allele group.
A*36 | A36 | A1 | Sample |
allele | % | % | size (N) |
*3601 | 68 | 16 | 807 |
A36 has a high false serotyping rate to A1.