HLA-A43

HLA-A43
(MHC Class I, A cell surface antigen)
HLA-A43
About
Protein	transmembrane receptor/ligand
Structure	αβ heterodimer
Subunits	HLA-A*4301, β2-microglobulin
Older names	A10
Subtypes
Subtype allele Available structures A43 *4301 {{{cNick2}}} *43{{{cAllele2}}} {{{cNick3}}} *43{{{cAllele3}}} {{{cNick4}}} *43{{{cAllele4}}}
Alleles link-out to IMGT/HLA database at EBI

HLA-A43 (A43) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α⁴³ subset of HLA-A α-chains. For A43, the alpha "A" chain are encoded by the HLA-A*43 allele group and the β-chain are encoded by B2M locus.^[1] This group currently is dominated by A*4301. A43 and A*43 are almost synonymous in meaning. A43 is a split antigen of the broad antigen serotype A10. A43 is a sister serotype of A25, A26, A34, and A66.

A43 is more common in Africa and SouthWest Asia. A43 is believed to have been formed by a single gene conversion between another HLA-A and the A*2601 allele.^[2].

A43 serotyping is poor.