HLA-A80 | ||||||||||||||||
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(MHC Class I, A cell surface antigen) | ||||||||||||||||
About | ||||||||||||||||
Protein | transmembrane receptor/ligand | |||||||||||||||
Structure | αβ heterodimer | |||||||||||||||
Subunits | HLA-A*8001, β2-microglobulin | |||||||||||||||
Older names | AX"BG" | |||||||||||||||
Subtypes | ||||||||||||||||
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Alleles link-out to IMGT/HLA database at EBI |
HLA-A80 (A80) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α80 subset of HLA-A α-chains. For A80, the alpha "A" chain are encoded by the HLA-A*80 allele group and the β-chain are encoded by B2M locus.[1] This group currently is dominated by A*8001. A80 and A*80 are almost synonymous in meaning.
A80 is more common in West Central Africa. A80 is the least common HLA-A allele group.
A*80 | A80 | A10 | Sample |
allele | % | % | size (N) |
*8001 | 36 | 10 | 505 |
A80 HLA-A80 typing is poor. Most typing is done with SSP-PCR. Most of 8001 are detected with "Blank" serotype..