HLA-DQ1

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major histocompatibility complex, class II, DQ1
Haplotypes	DQA1*0101:DQB1*0501 DQA1*0101:DQB1*0502 DQA1*0102:DQB1*0502 DQA1*0104:DQB1*0503 DQA1*0103:DQB1*0601 DQA1*0102:DQB1*0602 DQA1*0103:DQB1*0603 DQA1*0102:DQB1*0604 DQA1*0102:DQB1*0605 DQA1*0102:DQB1*0609....
Structure
Identifiers	alpha 1 *0101 *0102 *0103 *0104
Symbol(s)	HLA-DQA1[permanent dead link]
EBI-HLA	DQA1*0101
EBI-HLA	DQA1*0102 Archived 2011-05-15 at the Wayback Machine
EBI-HLA	DQA1*0103
EBI-HLA	DQA1*0104
Identifiers	beta 1 *05 or *06
Symbol(s)	HLA-DQB1
EBI-HLA	DQB1*05
EBI-HLA	DQB1*06
Shared data
Locus	chr.6 6p21.31

HLA-DQ1 is a serotype that covers a broad range of HLA-DQ haplotypes. Historically it was identified as a DR-like alpha chain called DC1;^[1] later, it was among 3 types DQw1 (later DQ1, and split into DQ5 and DQ6), DQw2 and DQw3. Of these three serotyping specificities only DQw1 recognized DQ alpha chain.^[2] The serotype is positive in individuals who bear the DQA1*01 alleles. The most frequently found within this group are: DQA1*0101, *0102, *0103, and *0104. In the illustration on the right, DQ1 serotyping antibodies recognizes the DQ α (magenta), where antibodies to DQA1* gene products bind variable regions close to the peptide binding pocket.