HLA-DQ7


major histocompatibility complex, class II, DQ7
Haplotypes	DQA103:02:DQB103:01 DQA103:03:DQB103:01 DQA104:01:DQB103:01 DQA105:05:DQB103:01 DQA106:01:DQB103:01
Structure (See HLA-DQ)
Identifiers	alpha 1 0302 0303 0401 0505 *0601
Symbol(s)	HLA-DQA1^{[permanent dead link]}
EBI-HLA	DQA1*0302
EBI-HLA	DQA1*0303
EBI-HLA	DQA1*0401
EBI-HLA	DQA1*0505
EBI-HLA	DQA1*0601
Identifiers	beta 1 0301 0304
Symbol(s)	HLA-DQB1
EBI-HLA	DQB1*0301
EBI-HLA	DQB1*0304
Shared data
Locus	chr.6 6p21.31

HLA-DQ7 (DQ7) is an HLA-DQ serotype that recognizes the common HLA DQB1*0301^[1] and the less common HLA DQB1*0304 gene products. DQ7 is a form of 'split antigen' of the broad antigen group DQ3 which also contains DQ8 and DQ9.

DQ7 is linked by haplotype to a number of DQA1 (DQ alpha chain) genes, producing in cis-haplotype form, a large number of DQ αβ isoforms. These DQ alpha chains are also known to form transhaplotype isomers with other HLA-DQ.

DQ7 is linked to the following alpha chains genes (DQA1*)

03 – *0301, *0302, *0303
0401
0505
0601

^ Bunce M, Taylor CJ, Welsh KI (1993). "Rapid HLA-DQB typing by eight polymerase chain reaction amplifications with sequence-specific primers (PCR-SSP)". Hum. Immunol. 37 (4): 201–6. doi:10.1016/0198-8859(93)90502-R. PMID 7905469.

[pmid7905469-1] Bunce M, Taylor CJ, Welsh KI (1993). "Rapid HLA-DQB typing by eight polymerase chain reaction amplifications with sequence-specific primers (PCR-SSP)". Hum. Immunol. 37 (4): 201–6. doi:10.1016/0198-8859(93)90502-R. PMID 7905469.

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