HLA-DRB5

HLA-DRB5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1FV1, 1H15, 1HQR, 1ZGL
Identifiers
Aliases	HLA-DRB5, HLA-DRB, major histocompatibility complex, class II, DR beta 5, HLA-DRB5*
External IDs	OMIM: 604776; MGI: 95901; HomoloGene: 101524; GeneCards: HLA-DRB5; OMA:HLA-DRB5 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	32,530,287 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	34,535,648 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; lymph node; ; appendix; ; duodenum; ; monocyte; ; upper lobe of left lung; ; right coronary artery; ; spleen; ; right lung; ; olfactory zone of nasal mucosa;
	Top expressed in
	mesenteric lymph nodes; ; spleen; ; thymus; ; submandibular gland; ; carotid body; ; right lung; ; lip; ; white adipose tissue; ; right lung lobe; ; tibiofemoral joint;
	More reference expression data
	n/a
Gene ontology
Molecular function	peptide antigen binding;
Cellular component	integral component of membrane; endocytic vesicle membrane; clathrin-coated endocytic vesicle membrane; endosome; Golgi apparatus; trans-Golgi network membrane; endoplasmic reticulum membrane; membrane; late endosome membrane; Golgi membrane; plasma membrane; transport vesicle membrane; MHC class II protein complex; lysosomal membrane; endoplasmic reticulum; ER to Golgi transport vesicle membrane; lysosome; integral component of lumenal side of endoplasmic reticulum membrane; endosome membrane; extracellular exosome;
Biological process	antigen processing and presentation; antigen processing and presentation of exogenous peptide antigen via MHC class II; interferon-gamma-mediated signaling pathway; immune system process; T cell costimulation; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; immune response; T cell receptor signaling pathway; adaptive immune response;
	Sources:Amigo / QuickGO
Orthologs
	3127
	14969
	ENSG00000198502
	ENSMUSG00000060586
	Q30154
P04231; P04230; P18468; P18469; O78196;
	n/a
	NM_002125
	NM_010382
	NP_002116
	NP_034512
	Wikidata
View/Edit Human	View/Edit Mouse

HLA class II histocompatibility antigen, DRB5 beta chain is a protein that in humans is encoded by the HLA-DRB5 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000198502 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000060586 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: HLA-DRB5 major histocompatibility complex, class II, DR beta 5".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000198502 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000060586 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[Entrez_Gene_3127-5] "Entrez Gene: HLA-DRB5 major histocompatibility complex, class II, DR beta 5".

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