HLA Informatics Group

The HLA Informatics Group (HIG) is a research group led by Professor Steven Marsh at the Anthony Nolan Research Institute that develops, runs and maintains the IMGT (immunogenetics)/HLA (Human leukocyte antigen) Database and the IPD (immuno polymorphism database). The IMGT/HLA database originated as part of IMGT and was merged with IPD in 2003.^[1] The IMGT/HLA Database is a central repository for sequences of the human major histocompatibility complex and currently contains over 5,000 allele sequences, including over 1,800 HLA-B sequences.

As well as sequence information, the IMGT/HLA Database and the IPD Databases include extensive information regarding the source material that sequences are derived from.^[2]

The IMGT/HLA website is the main source to know how many HLA alleles have been discovered.

^ Robinson, James; Barker, Dominic J; Georgiou, Xenia; Cooper, Michael A; Flicek, Paul; Marsh, Steven G E (2020). "IPD-IMGT/HLA Database". Nucleic Acids Research. 48 (D1): D948–D955. doi:10.1093/nar/gkz950. PMC 7145640. PMID 31667505.
^ About the Databases

[1] Robinson, James; Barker, Dominic J; Georgiou, Xenia; Cooper, Michael A; Flicek, Paul; Marsh, Steven G E (2020). "IPD-IMGT/HLA Database". Nucleic Acids Research. 48 (D1): D948–D955. doi:10.1093/nar/gkz950. PMC 7145640. PMID 31667505.

[2] About the Databases

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