HOT-2

HOT-2
Names
Preferred IUPAC name
2-[4-(Ethylsulfanyl)-2,5-dimethoxyphenyl]-N-hydroxyethan-1-amine
Other names
2-[4-(Ethylthio)-2,5-dimethoxyphenyl]ethanaminol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C12H19NO3S/c1-4-17-12-8-10(15-2)9(5-6-13-14)7-11(12)16-3/h7-8,13-14H,4-6H2,1-3H3 checkY
    Key: XGFJCRNRWOXGQM-UHFFFAOYSA-N checkY
  • InChI=1/C12H19NO3S/c1-4-17-12-8-10(15-2)9(5-6-13-14)7-11(12)16-3/h7-8,13-14H,4-6H2,1-3H3
    Key: XGFJCRNRWOXGQM-UHFFFAOYAO
  • CCSc1cc(OC)c(cc1OC)CCNO
Properties
C12H19NO3S
Molar mass 257.35 g·mol−1
Melting point 122 °C (252 °F; 395 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)

HOT-2 (2,5-dimethoxy-4-(β-ethylthio)-N-hydroxyphenethylamine) is a psychedelic phenethylamine of the 2C family. It was presumably first synthesized by Alexander Shulgin and reported in his book PiHKAL.[1]