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| Content | |
|---|---|
| Description | HGNC is responsible for approving unique symbols and names for human loci, including protein coding genes, RNA genes and pseudogenes, to allow unambiguous scientific communication. |
| Data types captured | Gene nomenclature |
| Organisms | Human |
| Contact | |
| Research center | EMBL-EBI, UK; |
| Primary citation | Braschi et al. (2019)[1] |
| Access | |
| Website | www www |
| Download URL | Statistics & Downloads Custom Downloads HGNC Biomart |
| Web service URL | rest |
| Tools | |
| Web | HGNC Comparison of Orthology Predictions,[2][3] Search |
| Miscellaneous | |
| Curation policy | Yes |
The HUGO Gene Nomenclature Committee (HGNC) is a committee of the Human Genome Organisation (HUGO) that sets the standards for human gene nomenclature. The HGNC approves a unique and meaningful name for every known human gene,[4][5] based on a query of experts. In addition to the name, which is usually 1 to 10 words long, the HGNC also assigns a symbol (a short group of characters) to every gene. As with an SI symbol, a gene symbol is like an abbreviation but is more than that, being a second unique name that can stand on its own just as much as substitute for the longer name. It may not necessarily "stand for" the initials of the name, although many gene symbols do reflect that origin.
- ^ Braschi B, Denny P, Gray K, Jones T, Seal R, Tweedie S, et al. (January 2019). "Genenames.org: the HGNC and VGNC resources in 2019". Nucleic Acids Research. 47 (D1): D786–D792. doi:10.1093/nar/gky930. PMC 6324057. PMID 30304474.
- ^ Wright MW, Eyre TA, Lush MJ, Povey S, Bruford EA (November 2005). "HCOP: the HGNC comparison of orthology predictions search tool". Mammalian Genome. 16 (11): 827–8. doi:10.1007/s00335-005-0103-2. PMID 16284797. S2CID 1091618.
- ^ Eyre TA, Wright MW, Lush MJ, Bruford EA (January 2007). "HCOP: a searchable database of human orthology predictions". Briefings in Bioinformatics. 8 (1): 2–5. doi:10.1093/bib/bbl030. PMID 16951416.
- ^ "About the HGNC | HUGO Gene Nomenclature Committee". Archived from the original on 2023-03-26. Retrieved 2018-03-23.
- ^ Bruford, Elspeth A.; Braschi, Bryony; Denny, Paul; Jones, Tamsin E. M.; Seal, Ruth L.; Tweedie, Susan (August 2020). "Guidelines for human gene nomenclature". Nature Genetics. 52 (8): 754–758. doi:10.1038/s41588-020-0669-3. PMC 7494048. PMID 32747822.