| Half and half nails | |
|---|---|
| Other names | Lindsay's nails |
 | |
| Half and half nails | |
| Specialty | Internal medicine, Dermatology |
| Causes | increased β-MSH |
| Risk factors | hemodialysis, renal transplant |
| Diagnostic method | Physical examination |
| Differential diagnosis | Terry's nails |
Half and half nails (also known as "Lindsay's nails") show the proximal portion of the nail white and the distal half red, pink, or brown, with a sharp line of demarcation between the two halves.[1]: 785 The darker distal discoloration does not fade on pressure,[2] which differentiates Lindsay's nails from Terry's nails. The discoloration is thought to be due to β-melanocyte–stimulating hormone.[2] Seventy percent of hemodialysis patients and 56% of renal transplant patients have at least one type of nail abnormality. Absence of lunula, splinter hemorrhage, and half and half nails were significantly more common in hemodialysis patients, while leukonychia was significantly more common in transplant patients.[1]: 785 [3]: 659
- ^ a b James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
- ^ a b Pitukweerakul, Siwadon; Pilla, Sree (2016-08-01). "Terry's Nails and Lindsay's Nails: Two Nail Abnormalities in Chronic Systemic Diseases". Journal of General Internal Medicine. 31 (8): 970–970. doi:10.1007/s11606-016-3628-z. ISSN 1525-1497. PMC 4945547. PMID 26902238.
- ^ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.