Harrisburg usually refers to the city of Harrisburg, Pennsylvania, in the United States, which is the capital of the state of Pennsylvania.
Harrisburg may also refer to:
- Harrisburg, Arkansas
- Harrisburg, Inyo County, California
- Harrisburg, Illinois
- Harrisburg, Indiana
- Harrisburg, Mississippi, town burned in the Civil War battle of Tupelo
- Harrisburg, Missouri
- Harrisburg, Nebraska
- Harrisburg, New York, town in Lewis County
- Harrisburg, Cattaraugus County, New York, hamlet in Allegany (town), New York
- Harrisburg, Warren County, New York, hamlet in town of Stony Creek, New York
- Harrisburg, North Carolina
- Harrisburg, Ohio, a village in Franklin and Pickaway counties
- Harrisburg, Gallia County, Ohio
- Harrisburg, Stark County, Ohio
- Harrisburg, Oregon
- Harrisburg, Pennsylvania
- Harrisburg, South Dakota
- Harrisburg, Houston, former city in Texas
- Harrisburg, Utah, a ghost town
- Harrisburg, Virginia