Harrison is a Roanoke, Virginia neighborhood located in central Roanoke, that initially developed in the 1920s as an early Roanoke suburb. It borders the neighborhoods of Melrose-Rugby and Washington Park on the north, Gilmer on the south, Gainsboro on the east and Loudon-Melrose on the west.[1] Its northern boundary is concurrent with U.S. Route 460 (Melrose/Orange Avenue), and as of the 2000 Census Harrison has a population of 1,019 residents with 393 households.[2]