"He Ain't Heavy, He's My Brother" is a 1969 song by the band the Hollies.
He Ain't Heavy, He's My Brother may also refer to:
- He Ain't Heavy, He's My Brother (album), a 1969 Hollies album, also known as Hollies Sing Hollies and including the song of the same name
- He Ain't Heavy, He's My Brother (film), a Hong Kong film, also known as He Ain't Heavy, He's My Father or 新難兄難弟
- "He Ain't Heavy, He's My Brother", an episode of Rizzoli & Isles
- "He Ain't Heavy, He's My Brother", an episode of On Our Own (1994 TV series)
- The caption of a logo adopted by Boys Town in 1943