| Helicobacter hepaticus | |
|---|---|
Scientific classification 
| |
| Domain: | Bacteria |
| Phylum: | Campylobacterota |
| Class: | "Campylobacteria" |
| Order: | Campylobacterales |
| Family: | Helicobacteraceae |
| Genus: | Helicobacter |
| Species: | H. hepaticus
|
| Binomial name | |
| Helicobacter hepaticus Fox et al., 1994
| |
Helicobacter hepaticus is a bacterium in the Helicobacteraceae family, Campylobacterales order.[1]
It has a spiral shape and bipolar, single, sheathed flagellum. The bacterium was first isolated from the livers of mice with active, chronic hepatitis. Other organs the bacterium colonize include the cecal and colonic mucosae of mice. It elicits persistent hepatitis in mice and has been associated with colorectal cancer and other diseases.[2][3] Its genome has been sequenced and is 1,799,146 bases long with 1,875 coding sequences.[4]
- ^ Fox JG, Dewhirst FE, Tully JG, et al. (May 1994). "Helicobacter hepaticus sp. nov., a microaerophilic bacterium isolated from livers and intestinal mucosal scrapings from mice". Journal of Clinical Microbiology. 32 (5): 1238–45. doi:10.1128/JCM.32.5.1238-1245.1994. PMC 263656. PMID 8051250.
- ^ Fox, J G; Ge, Z; Whary, M T; Erdman, S E; Horwitz, B H (2010). "Helicobacter hepaticus infection in mice: models for understanding lower bowel inflammation and cancer" (PDF). Mucosal Immunology. 4 (1): 22–30. doi:10.1038/mi.2010.61. ISSN 1933-0219. PMC 3939708. PMID 20944559.
- ^ Shames B, Fox JG, Dewhirst F, Yan L, Shen Z, Taylor NS (November 1995). "Identification of widespread Helicobacter hepaticus infection in feces in commercial mouse colonies by culture and PCR assay". Journal of Clinical Microbiology. 33 (11): 2968–72. doi:10.1128/JCM.33.11.2968-2972.1995. PMC 228616. PMID 8576355.
- ^ Suerbaum, Sebastian (2003). "The complete genome sequence of the carcinogenic bacterium Helicobacter hepaticus". PNAS. 100 (13): 7901–7906. Bibcode:2003PNAS..100.7901S. doi:10.1073/pnas.1332093100. PMC 164685. PMID 12810954.