Hepatitis C virus (HCV) cis-acting replication element (CRE) | |
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Identifiers | |
Symbol | HepC_CRE |
Rfam | RF00260 |
Other data | |
RNA type | Cis-reg |
Domain(s) | Viruses |
SO | SO:0000233 |
PDB structures | PDBe |
The Hepatitis C virus (HCV) cis-acting replication element (CRE) is an RNA element which is found in the coding region of the RNA-dependent RNA polymerase NS5B. Mutations in this family have been found to cause a blockage in RNA replication and it is thought that both the primary sequence and the structure of this element are crucial for HCV RNA replication.[1]