Highway 222[1] is a highway of northeastern Thailand. It begins at Phang Khon in Sakhon Nakhon Province at 17°23′20″N 103°43′17″E / 17.38889°N 103.72139°E, where it meets Highway 227 and Highway 22 and ends near the Mekong River on the Lao border in the north at Bueng Kan in Bueng Kan Province at 18°21′39″N 103°38′47″E / 18.36083°N 103.64639°E, where it joins Highway 212.[2]