Hiss or Hissing may refer to:
- Hiss (electromagnetic), a wave generated in the plasma of the Earth's ionosphere or magnetosphere
- Hiss (surname)
- Hissing (manhwa), a Korean manhwa series by Kang EunYoung
- Noise (electronics) or electronic circuit hiss, white noise present at low level in all electronic circuits
- Sibilant, a group of consonants that have a hissing or hushing sound
- Tape hiss, high-frequency noise on analogue magnetic tape recordings
- The Hiss, a five piece rock band from Atlanta, Georgia
- Honda Ignition Security System, a vehicle immobiliser
- A sound made by snakes, cats and various other animals as a warning; see list of animal sounds
- "Hiss" (song), a 2024 song by Megan Thee Stallion