The Holmes rebound phenomenon is a reflex that occurs when one attempts to move a limb against resistance that is suddenly removed.[1] When the resistance is removed, the limb will usually move a short distance in the original direction, at which point the antagonist muscles will contract, causing the muscle to yank back in the opposite direction.[2] The phenomenon will be present in limbs unaffected by disease or illness, and strongly exaggerated in limbs exhibiting signs of spasticity. A complete absence of the phenomenon (that is, a failure of the antagonist muscles to contract) may indicate the presence of cerebellar disease.[1] Therefore, an awareness of the phenomenon can assist in the diagnoses of both types of disorders.
The phenomenon was first described by Gordon Morgan Holmes and Thomas Grainger Stewart in a paper published in 1904, though it was not named until a 1917 paper published by Holmes.[3]