| Human T-lymphotropic virus 2 | |
|---|---|
| Specialty | Infectious diseases |
| Symptoms | Mild cognitive Impairment, Mycosis fungoides |
| Duration | Chronic, incurable |
| Causes | HTLV-2 |
| Risk factors | Unsafe sex, haemophiliacs |
| Diagnostic method | Blood test |
| Differential diagnosis | HIV/AIDS, Lymphoma, HTLV-1 |
| Prevention | Practicing safe-sex, use of clean needles, screening blood transfusions, Avoiding breastfeeding. |
| Medication | Antiretrovirals, chemotherapy |
| Prognosis | 95% present with no symptoms, generally good |
| Frequency | 15-20 million people worldwide |
| Primate T-lymphotropic virus 2 | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Pararnavirae |
| Phylum: | Artverviricota |
| Class: | Revtraviricetes |
| Order: | Ortervirales |
| Family: | Retroviridae |
| Genus: | Deltaretrovirus |
| Species: | Primate T-lymphotropic virus 2
|
A virus closely related to HTLV-I, human T-lymphotropic virus 2 (HTLV-II) shares approximately 70% genomic homology (structural similarity) with HTLV-I. It was discovered by Robert Gallo and colleagues.[1][2]
HTLV-2 is prevalent among the indigenous populations in Africa and the Indian-American tribes in Central and South America as well as among drug users in Europe and North America[3] It can be passed down from mother to child through breastmilk and genetically as well from either parent.
HTLV-II entry in target cells is mediated by the glucose transporter GLUT1.[4]
- ^ Geskin, Larisa J.; Pomerantz, Rebecca G.; Mirvish, Ezra D. (2011-02-01). "Infectious agents in cutaneous T-cell lymphoma". Journal of the American Academy of Dermatology. 64 (2): 423–431. doi:10.1016/j.jaad.2009.11.692. ISSN 0190-9622. PMC 3954537. PMID 20692726.
- ^ "Robert gallo discovers htlv2 and 1". Retrieved 23 February 2019.
- ^ Ciminale, Vincenzo; Rende, Francesca; Bertazzoni, Umberto; Romanelli, Maria G. (2014-07-29). "HTLV-1 and HTLV-2: highly similar viruses with distinct oncogenic properties". Frontiers in Microbiology. 5: 398. doi:10.3389/fmicb.2014.00398. ISSN 1664-302X. PMC 4114287. PMID 25120538.
- ^ Manel N, Kim FJ, Kinet S, Taylor N, Sitbon M, Battini JL (November 2003). "The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV". Cell. 115 (4): 449–59. doi:10.1016/S0092-8674(03)00881-X. PMID 14622599.