Hydrogel

Gelatin, here in sheets for cooking, is a hydrogel.
Peptide hydrogel formation shown by the inverted vial method.

A hydrogel is a biphasic material, a mixture of porous and permeable solids and at least 10% of water or other interstitial fluid.[1][2] The solid phase is a water insoluble three dimensional network of polymers, having absorbed a large amount of water or biological fluids.[2][3][4][5] Hydrogels have several applications, especially in the biomedical area, such as in hydrogel dressing. Many hydrogels are synthetic, but some are derived from natural materials.[6][7] The term "hydrogel" was coined in 1894.[8]

IUPAC definition for a hydrogel
  1. ^ Wichterle, O.; Lím, D. (1960-01-01). "Hydrophilic Gels for Biological Use". Nature. 185 (4706): 117–118. Bibcode:1960Natur.185..117W. doi:10.1038/185117a0. ISSN 0028-0836. S2CID 4211987.
  2. ^ a b Ghosh, Shampa; Ghosh, Soumya; Sharma, Hitaishi; Bhaskar, Rakesh; Han, Sung Soo; Sinha, Jitendra Kumar (2024-01-01). "Harnessing the power of biological macromolecules in hydrogels for controlled drug release in the central nervous system: A review". International Journal of Biological Macromolecules. 254: 127708. doi:10.1016/j.ijbiomac.2023.127708. ISSN 0141-8130. S2CID 264944892.
  3. ^ Shrivastava, Priya; Vishwakarma, Nikhar; Gautam, Laxmikant; Vyas, Suresh P. (2023), "Magnetically responsive polymeric gels and elastomeric system(s) for drug delivery", Smart Polymeric Nano-Constructs in Drug Delivery, Elsevier, pp. 129–150, doi:10.1016/b978-0-323-91248-8.00012-x, ISBN 978-0-323-91248-8, retrieved 2023-01-16
  4. ^ Fundamental Biomaterials: Polymers. 2018. doi:10.1016/c2016-0-03544-1. ISBN 9780081021941.
  5. ^ Polymer Science: A Comprehensive Reference. Elsevier. 2012. doi:10.1016/c2009-1-28406-1. ISBN 978-0-08-087862-1.
  6. ^ Cai W, Gupta RB (2012). "Hydrogels". Kirk-Othmer Encyclopedia of Chemical Technology. pp. 1–20. doi:10.1002/0471238961.0825041807211620.a01.pub2. ISBN 978-0471238966.
  7. ^ Cite error: The named reference :2 was invoked but never defined (see the help page).
  8. ^ Bemmelen JM (1907). "Der Hydrogel und das kristallinische Hydrat des Kupferoxydes". Zeitschrift für Chemie und Industrie der Kolloide. 1 (7): 213–214. doi:10.1007/BF01830147. S2CID 197928622.