| Hyperuricosuria | |
|---|---|
 | |
| Uric acid | |
| Specialty | Nephrology, urology |
Hyperuricosuria is a medical term referring to the presence of excessive amounts of uric acid in the urine. For men this is at a rate greater than 800 mg/day, and for women, 750 mg/day.[1] Notable direct causes of hyperuricosuria are dissolution of uric acid crystals in the kidneys or urinary bladder, and hyperuricemia. Notable indirect causes include uricosuric drugs, rapid breakdown of bodily tissues containing large quantities of DNA and RNA, and a diet high in purine.
Medications that may contribute to the cure or amelioration of hyperuricosuria include allopurinol which acts by inhibiting xanthine oxidase and reducing uric acid production.[2] Hyperuricosuria may be a medical sign of:
- Gout (very common)
- Kidney stones of uric acid (uric acid nephrolithiasis)
- Acute uric acid nephropathy
- Acute kidney failure
- Tumor lysis syndrome
- Fanconi syndrome
- Dent's disease (very rare)
- ^ "Hyperuricosuria and Gouty Diathesis". Medscape, WebMD Ltd. 2016. Retrieved 1 April 2013.
- ^ "Allopurinol". MedlinePlus, National Library of Medicine, US National Institutes of Health. 2016. Retrieved 24 December 2016.