ID4 is a protein coding gene. In humans, it encodes the protein known as DNA-binding protein inhibitor ID-4.[5][6] This protein is known to be involved in the regulation of many cellular processes during both prenatal development and tumorigenesis. This is inclusive of embryonic cellular growth, senescence, cellular differentiation, apoptosis, and as an oncogene in angiogenesis.[7]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000172201 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021379 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Pagliuca A, Bartoli PC, Saccone S, Della Valle G, Lania L (Oct 1995). "Molecular cloning of ID4, a novel dominant negative helix-loop-helix human gene on chromosome 6p21.3-p22". Genomics. 27 (1): 200–3. doi:10.1006/geno.1995.1026. PMID 7665172.
- ^ "Entrez Gene: ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein".
- ^ "Atlas of Genetics and Cytogenetics in Oncology and Haematology".