IDPN
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Names
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Preferred IUPAC name
3,3′-Azanediyldipropanenitrile
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Other names
Bis(2-cyanoethyl)amine
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Identifiers
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ChemSpider
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ECHA InfoCard
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100.003.566
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EC Number
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UNII
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UN number
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3334
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InChI=1S/C6H9N3/c7-3-1-5-9-6-2-4-8/h9H,1-2,5-6H2 Key: SBAJRGRUGUQKAF-UHFFFAOYSA-N
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Properties
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C6H9N3
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Molar mass
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123.159 g·mol−1
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Density
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1.02
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Melting point
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−5.5 °C (22.1 °F; 267.6 K)
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Hazards
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GHS labelling:
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Warning
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H315, H319, H335
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P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
IDPN (3,3'-iminodipropanenitrile) is a neurotoxin with ototoxic and hepatotoxic effects. It causes irreversible movement disorder.[1][2][3]
- ^ Sedó-Cabezón, Lara; Jedynak, Paulina; Boadas-Vaello, Pere; Llorens, Jordi (1 October 2015). "Transient alteration of the vestibular calyceal junction and synapse in response to chronic ototoxic insult in rats". Disease Models & Mechanisms. 8 (10): 1323–1337. doi:10.1242/dmm.021436. PMC 4610239. PMID 26398945.
- ^ Khan, HA; Ibrahim, KE (12 October 2015). "Pattern of neurobehavioral and organ-specific toxicities of β, β'-iminodipropionitrile in mice". Archives of Medical Science. 11 (5): 1137–44. doi:10.5114/aoms.2015.54871 (inactive 1 November 2024). PMC 4624758. PMID 26528360.
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: CS1 maint: DOI inactive as of November 2024 (link)
- ^ Ogata, Keiko; Kushida, Masahiko; Miyata, Kaori; Sumida, Kayo; Takeda, Shuji; Izawa, Takeshi; Kuwamura, Mitsuru; Yamate, Jyoji (2016). "Alteration of microRNA expressions in the pons and medulla in rats after 3,3′-iminodipropionitrile administration". Journal of Toxicologic Pathology. 29 (4): 229–236. doi:10.1293/tox.2016-0019. PMC 5097965. PMID 27821907.