IFNA21

IFNA21
Identifiers
Aliases	IFNA21, IFN-alphaI, LeIF F, leIF-F, interferon, alpha 21, interferon alpha 21
External IDs	OMIM: 147584; MGI: 2667155; HomoloGene: 88661; GeneCards: IFNA21; OMA:IFNA21 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	21,166,660 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	88,562,696 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; right hemisphere of cerebellum; ; Brodmann area 9; ; hypothalamus; ; Cortex of frontal lobe; ; prefrontal cortex; ; lymph node; ; nucleus accumbens; ; islet of Langerhans; ; mesencephalon;
	Top expressed in
	embryo; ; embryo;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	cytokine activity; type I interferon receptor binding; cytokine receptor binding;
Cellular component	extracellular region; extracellular space;
Biological process	natural killer cell activation involved in immune response; B cell differentiation; defense response; B cell proliferation; blood coagulation; positive regulation of peptidyl-serine phosphorylation of STAT protein; humoral immune response; adaptive immune response; defense response to virus; type I interferon signaling pathway; response to exogenous dsRNA; T cell activation involved in immune response; cytokine-mediated signaling pathway; innate immune response; regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	3452
	230396
	ENSG00000137080
	ENSMUSG00000063376
	P01568
	Q80SU4
	NM_002175
	NM_177347
	NP_002166
	NP_796321
	Wikidata
View/Edit Human	View/Edit Mouse

Interferon alpha-21 is a protein that in humans is encoded by the IFNA21 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000137080 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000063376 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO (Dec 1992). "Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia". Genomics. 14 (2): 437–43. doi:10.1016/S0888-7543(05)80238-1. PMID 1385305.
^ "Entrez Gene: IFNA21 interferon, alpha 21".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000137080 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000063376 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1385305-5] Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO (Dec 1992). "Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia". Genomics. 14 (2): 437–43. doi:10.1016/S0888-7543(05)80238-1. PMID 1385305.

[entrez-6] "Entrez Gene: IFNA21 interferon, alpha 21".

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