IGFBP6

IGFBP6
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1RMJ
Identifiers
Aliases	IGFBP6, IBP6, insulin like growth factor binding protein 6
External IDs	OMIM: 146735; MGI: 96441; HomoloGene: 1641; GeneCards: IGFBP6; OMA:IGFBP6 - orthologs
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	102,057,946 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; tibial nerve; ; gastric mucosa; ; canal of the cervix; ; left uterine tube; ; right coronary artery; ; thoracic aorta; ; ascending aorta; ; trigeminal ganglion; ; left coronary artery;
	Top expressed in
	ankle; ; uterus; ; right lung; ; right lung lobe; ; ankle joint; ; cervix; ; left lung; ; lip; ; white adipose tissue; ; esophagus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	insulin-like growth factor binding; signaling receptor binding; growth factor binding; insulin-like growth factor I binding; insulin-like growth factor II binding; fibronectin binding;
Cellular component	cytoplasm; Golgi apparatus; extracellular region; extracellular space; insulin-like growth factor binary complex;
Biological process	regulation of insulin-like growth factor receptor signaling pathway; negative regulation of canonical Wnt signaling pathway; regulation of cell growth; signal transduction; negative regulation of cell population proliferation;
	Sources:Amigo / QuickGO
Orthologs
	3489
	16012
	n/a
	ENSMUSG00000023046
	P24592
	P47880
	NM_002178
	NM_008344
	NP_002169
	NP_032370
	Wikidata
View/Edit Human	View/Edit Mouse

Insulin-like growth factor-binding protein 6 (IGFBP-6) is a protein that in humans is encoded by the IGFBP6 gene.^[4]^[5]^[6]

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000023046 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kiefer MC, Ioh RS, Bauer DM, Zapf J (May 1991). "Molecular cloning of a new human insulin-like growth factor binding protein". Biochem Biophys Res Commun. 176 (1): 219–25. doi:10.1016/0006-291X(91)90912-Q. PMID 1850258.
^ Ehrenborg E, Zazzi H, Lagercrantz S, Granqvist M, Hillerbrand U, Allander SV, Larsson C, Luthman H (May 1999). "Characterization and chromosomal localization of the human insulin-like growth factor-binding protein 6 gene". Mamm Genome. 10 (4): 376–80. doi:10.1007/s003359901005. PMID 10087296. S2CID 21499958.
^ "Entrez Gene: IGFBP6 insulin-like growth factor binding protein 6".

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000023046 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1850258-4] Kiefer MC, Ioh RS, Bauer DM, Zapf J (May 1991). "Molecular cloning of a new human insulin-like growth factor binding protein". Biochem Biophys Res Commun. 176 (1): 219–25. doi:10.1016/0006-291X(91)90912-Q. PMID 1850258.

[pmid10087296-5] Ehrenborg E, Zazzi H, Lagercrantz S, Granqvist M, Hillerbrand U, Allander SV, Larsson C, Luthman H (May 1999). "Characterization and chromosomal localization of the human insulin-like growth factor-binding protein 6 gene". Mamm Genome. 10 (4): 376–80. doi:10.1007/s003359901005. PMID 10087296. S2CID 21499958.

[entrez-6] "Entrez Gene: IGFBP6 insulin-like growth factor binding protein 6".

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