IGHV@

IGHV@
Identifiers
Aliases
External IDsGeneCards: [1]; OMA:- orthologs
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Ig heavy chain V-III region VH26 is a protein that in humans is encoded by the IGHV@ gene.[1][2][3]

IGHV is the immunoglobulin heavy chain variable region genes; in B-cell neoplasms like chronic lymphocytic leukemia, mutations of IGHV are associated with better responses to some treatments and with prolonged survival.[4]

  1. ^ Walter MA, Dosch HM, Cox DW (Aug 1991). "A deletion map of the human immunoglobulin heavy chain variable region". J Exp Med. 174 (2): 335–49. doi:10.1084/jem.174.2.335. PMC 2118905. PMID 1649888.
  2. ^ Schroeder HW Jr; Walter MA; Hofker MH; Ebens A; Willems van Dijk K; Liao LC; Cox DW; Milner EC; Perlmutter RM (Dec 1988). "Physical linkage of a human immunoglobulin heavy chain variable region gene segment to diversity and joining region elements". Proc Natl Acad Sci U S A. 85 (21): 8196–200. Bibcode:1988PNAS...85.8196S. doi:10.1073/pnas.85.21.8196. PMC 282394. PMID 3141924.
  3. ^ "Entrez Gene: IGHV@ immunoglobulin heavy variable group".
  4. ^ Forconi F, Sozzi E, Cencini E, et al. (November 2009). "Hairy cell leukemias with unmutated IGHV genes define the minor subset refractory to single agent cladribine and with more aggressive behavior". Blood. 114 (21): 4696–4702. doi:10.1182/blood-2009-03-212449. PMID 19667403.