IGSF1

IGSF1
Identifiers
Aliases	IGSF1, CHTE, IGCD1, IGDC1, INHBP, PGSF2, p120, immunoglobulin superfamily member 1
External IDs	OMIM: 300137; MGI: 2147913; HomoloGene: 1195; GeneCards: IGSF1; OMA:IGSF1 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	131,578,899 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	48,886,626 bp
RNA expression pattern
	Top expressed in
	pituitary gland; ; anterior pituitary; ; right auricle; ; hypothalamus; ; tibial nerve; ; nucleus accumbens; ; apex of heart; ; left testis; ; right testis; ; substantia nigra;
	Top expressed in
	arcuate nucleus; ; median eminence; ; dorsomedial hypothalamic nucleus; ; ventromedial nucleus; ; suprachiasmatic nucleus; ; dorsal tegmental nucleus; ; mammillary body; ; lateral hypothalamus; ; lumbar subsegment of spinal cord; ; ventral tegmental area;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	inhibin binding; protein binding; coreceptor activity; activin receptor antagonist activity;
Cellular component	integral component of membrane; extracellular region; membrane;
Biological process	regulation of transcription, DNA-templated; signal transduction; negative regulation of activin receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	3547
	209268
	ENSG00000147255
	ENSMUSG00000031111
	Q8N6C5
	Q7TQA1
	NM_001170961; NM_001170962; NM_001170963; NM_001555; NM_205833
	NM_177591; NM_177915; NM_183335; NM_183336
	NP_001164432; NP_001164433; NP_001164434; NP_001546; NP_991402
	NP_808259; NP_808583; NP_899178; NP_899179
	Wikidata
View/Edit Human	View/Edit Mouse

Immunoglobulin superfamily, member 1^[5] is a plasma membrane glycoprotein encoded by the IGSF1 gene,^[6]^[7]^[8] which maps to the X chromosome in humans and other mammalian species.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000147255 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031111 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entry 300137: Immunoglobulin superfamily, member 1; IGSF1".
^ Mazzarella R, Pengue G, Jones J, Jones C, Schlessinger D (Mar 1998). "Cloning and expression of an immunoglobulin superfamily gene (IGSF1) in Xq25". Genomics. 48 (2): 157–62. doi:10.1006/geno.1997.5156. PMID 9521868.
^ Frattini A, Faranda S, Redolfi E, Allavena P, Vezzoni P (Jul 1998). "Identification and genomic organization of a gene coding for a new member of the cell adhesion molecule family mapping to Xq25". Gene. 214 (1–2): 1–6. doi:10.1016/S0378-1119(98)00253-4. PMID 9729118.
^ "Entrez Gene: IGSF1 immunoglobulin superfamily, member 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000147255 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031111 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[OMIM_Entry_300137-5] "Entry 300137: Immunoglobulin superfamily, member 1; IGSF1".

[pmid9521868-6] Mazzarella R, Pengue G, Jones J, Jones C, Schlessinger D (Mar 1998). "Cloning and expression of an immunoglobulin superfamily gene (IGSF1) in Xq25". Genomics. 48 (2): 157–62. doi:10.1006/geno.1997.5156. PMID 9521868.

[pmid9729118-7] Frattini A, Faranda S, Redolfi E, Allavena P, Vezzoni P (Jul 1998). "Identification and genomic organization of a gene coding for a new member of the cell adhesion molecule family mapping to Xq25". Gene. 214 (1–2): 1–6. doi:10.1016/S0378-1119(98)00253-4. PMID 9729118.

[entrez-8] "Entrez Gene: IGSF1 immunoglobulin superfamily, member 1".

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