 | This article has multiple issues. Please help improve it or discuss these issues on the talk page. (Learn how and when to remove these messages)
|
| IMES-5 | |
|---|---|
 Consensus secondary structure and sequence conservation of IMES-5 RNA | |
| Identifiers | |
| Symbol | IMES-5 |
| Rfam | RF02995 |
| Other data | |
| RNA type | Gene; sRNA |
| SO | SO:0001263 |
| PDB structures | PDBe |
The IMES-5 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] These RNAs are present in environmental sequences, and have not yet (as of 2018) been identified in a classified organism.
It is ambiguous whether IMES-5 RNAs function as cis-regulatory elements or whether they operate in trans. The RNAs are often found upstream of genes that encode an acyl-tRNA synthetase that is specific for tryptophan. However, this association is not consistent to declare a cis-regulatory function for the RNA, and so it might function as a small RNA.
- ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.