IRF9

IRF9
Identifiers
Aliases	IRF9, IRF-9, ISGF3, ISGF3G, p48, interferon regulatory factor 9
External IDs	OMIM: 147574; MGI: 107587; HomoloGene: 4436; GeneCards: IRF9; OMA:IRF9 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	24,166,565 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	55,847,487 bp
RNA expression pattern
	Top expressed in
	spleen; ; granulocyte; ; appendix; ; lymph node; ; blood; ; gallbladder; ; right uterine tube; ; anterior pituitary; ; bone marrow; ; bone marrow cells;
	Top expressed in
	granulocyte; ; Ileal epithelium; ; spleen; ; lymph node; ; seminal vesicula; ; mesenteric lymph nodes; ; thymus; ; blood; ; left lung lobe; ; parotid gland;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Cellular component	nucleus; nucleoplasm; cytoplasm; cytosol;
Biological process	cell surface receptor signaling pathway; regulation of transcription, DNA-templated; transcription by RNA polymerase II; defense response to virus; type I interferon signaling pathway; transcription, DNA-templated; interferon-gamma-mediated signaling pathway; regulation of transcription by RNA polymerase II; immune system process;
	Sources:Amigo / QuickGO
Orthologs
	10379
	16391
	ENSG00000213928; ENSG00000285048
	ENSMUSG00000002325
	Q00978
	Q61179
	NM_006084; NM_001385400; NM_001385401; NM_001385402
	NM_001159417; NM_001159418; NM_008394
	NP_006075
	NP_001152889; NP_001152890; NP_032420
	Wikidata
View/Edit Human	View/Edit Mouse

Interferon regulatory factor 9 is a protein that in humans is encoded by the IRF9 gene, previously known as ISGF3G.^[5]^[6]^[7]

^ ^a ^b ^c ENSG00000285048 GRCh38: Ensembl release 89: ENSG00000213928, ENSG00000285048 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000002325 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Veals SA, Schindler C, Leonard D, Fu XY, Aebersold R, Darnell JE Jr, Levy DE (Aug 1992). "Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins". Mol Cell Biol. 12 (8): 3315–24. doi:10.1128/MCB.12.8.3315. PMC 364572. PMID 1630447.
^ McCusker D, Wilson M, Trowsdale J (Jun 1999). "Organization of the genes encoding the human proteasome activators PA28alpha and beta". Immunogenetics. 49 (5): 438–45. doi:10.1007/s002510050517. PMID 10199920. S2CID 40575791.
^ "Entrez Gene: ISGF3G interferon-stimulated transcription factor 3, gamma 48kDa".

[refGRCh38Ensembl-1] ENSG00000285048 GRCh38: Ensembl release 89: ENSG00000213928, ENSG00000285048 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000002325 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1630447-5] Veals SA, Schindler C, Leonard D, Fu XY, Aebersold R, Darnell JE Jr, Levy DE (Aug 1992). "Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins". Mol Cell Biol. 12 (8): 3315–24. doi:10.1128/MCB.12.8.3315. PMC 364572. PMID 1630447.

[pmid10199920-6] McCusker D, Wilson M, Trowsdale J (Jun 1999). "Organization of the genes encoding the human proteasome activators PA28alpha and beta". Immunogenetics. 49 (5): 438–45. doi:10.1007/s002510050517. PMID 10199920. S2CID 40575791.

[entrez-7] "Entrez Gene: ISGF3G interferon-stimulated transcription factor 3, gamma 48kDa".

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