Ichthyosis

Ichthyosis
Other namesIchthyoses
Ichthyosis is characterized by generalised, scaly skin.
SpecialtyDermatology

Ichthyosis (also named fish scale disease)[1] is a family of genetic skin disorders characterized by dry, thickened, scaly skin.[2] The more than 20 types of ichthyosis range in severity of symptoms, outward appearance, underlying genetic cause and mode of inheritance (e.g., dominant, recessive, autosomal or X-linked).[3] Ichthyosis comes from Greek ἰχθύς (ichthys) 'fish', since dry, scaly skin is the defining feature of all forms of ichthyosis.[4]

The severity of symptoms can vary enormously, from the mildest, most common, types such as ichthyosis vulgaris, which may be mistaken for normal dry skin, up to life-threatening conditions such as harlequin-type ichthyosis. Ichthyosis vulgaris accounts for more than 95% of cases.[5]

  1. ^ Dorf, Inger LH; Schmidt, Sigrún AJ; Sommerlund, Mette; Koppelhus, Uffe (November 2021). "Validity of First-Time Diagnoses of Darier's Disease in the Danish National Patient Registry". Clinical Epidemiology. 13: 1063–1069. doi:10.2147/clep.s326518. ISSN 1179-1349. PMC 8594618. PMID 34795531.
  2. ^ James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "27. Genodermatoses and congenital anomalies". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. pp. 563–565. ISBN 978-0-323-54753-6.
  3. ^ thefreedictionary.com/ichthyosis citing: Gale Encyclopedia of Medicine. Copyright 2008
  4. ^ "Ichthyosis". Health Information Library. Johns Hopkins Medicine. Archived from the original on 2 February 2009.
  5. ^ Okulicz JF, Schwartz RA (2003). "Hereditary and acquired ichthyosis vulgaris". International Journal of Dermatology. 42 (2): 95–8. doi:10.1046/j.1365-4362.2003.01308.x. PMID 12708996. S2CID 20029085.