Idiopathic generalized epilepsy

Idiopathic generalized epilepsy
SpecialtyNeurology

Idiopathic generalized epilepsy (IGE) is a group of epileptic disorders that are believed to have a strong underlying genetic basis. IGE is considered a subgroup of Genetic Generalized Epilepsy (GGE).[1] Patients with an IGE subtype are typically otherwise normal and have no structural brain abnormalities. People also often have a family history of epilepsy and seem to have a genetically predisposed risk of seizures. IGE tends to manifest itself between early childhood and adolescence although it can be eventually diagnosed later. The genetic cause of some IGE types is known, though inheritance does not always follow a simple monogenic mechanism.

  1. ^ Hirsch, Edouard; French, Jacqueline; Scheffer, Ingrid E.; Bogacz, Alicia; Alsaadi, Taoufik; Sperling, Michael R.; Abdulla, Fatema; Zuberi, Sameer M.; Trinka, Eugen; Specchio, Nicola; Somerville, Ernest; Samia, Pauline; Riney, Kate; Nabbout, Rima; Jain, Satish; Wilmshurst, Jo M.; Auvin, Stephane; Wiebe, Samuel; Perucca, Emilio; Moshé, Solomon L.; Tinuper, Paolo; Wirrell, Elaine C. (2022). "ILAE definition of the Idiopathic Generalized Epilepsy Syndromes: Position statement by the ILAE Task Force on Nosology and Definitions". Epilepsia. 63 (6): 1475–1499. doi:10.1111/epi.17236. ISSN 1528-1167. PMID 35503716.