Indocyanine green angiography

Indocyanine green angiography
Choroidal blood flow revealed with indocyanine green angiography
ICD-9-CM95.11

Indocyanine green angiography (ICGA) is a diagnostic procedure used to examine choroidal blood flow and associated pathology. Indocyanine green (ICG) is a water soluble cyanine dye which shows fluorescence in near-infrared (790–805 nm) range, with peak spectral absorption of 800-810 nm in blood.[1][2] The near infrared light used in ICGA penetrates ocular pigments such as melanin and xanthophyll, as well as exudates and thin layers of sub-retinal vessels.[3] Age-related macular degeneration is the third main cause of blindness worldwide, and it is the leading cause of blindness in industrialized countries.[4] Indocyanine green angiography is widely used to study choroidal neovascularization in patients with exudative age-related macular degeneration.[5] In nonexudative AMD, ICGA is used in classification of drusen and associated subretinal deposits.[5]

  1. ^ "Indocyanine Green Angiography". www.aao.org.
  2. ^ Khurana, AK (31 August 2015). "Ocular therapeutics". Comprehensive ophthalmology (6th ed.). Jaypee, The Health Sciences Publisher. p. 460. ISBN 978-93-5152-657-5.
  3. ^ John F, Salmon (2020). "Uveitis". Kanski's clinical ophthalmology : a systematic approach (9th ed.). Elsevier. p. 431. ISBN 978-0-7020-7711-1.
  4. ^ "Priority eye diseases". www.who.int. Archived from the original on March 22, 2006.
  5. ^ a b Cite error: The named reference AMDBook was invoked but never defined (see the help page).