| Interleukin-4 receptor alpha chain, N-terminal | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 interleukin-4 / receptor alpha chain complex | |||||||||
| Identifiers | |||||||||
| Symbol | IL4Ra_N | ||||||||
| Pfam | PF09238 | ||||||||
| InterPro | IPR015319 | ||||||||
| SCOP2 | 1iar / SCOPe / SUPFAM | ||||||||
| |||||||||
The interleukin 4 receptor is a type I cytokine receptor. It is a heterodimer, that is, composed of two subunits. IL4R is the human gene coding for IL-4Rα, the subunit which combines with either common gamma chain (γc, forming the type I IL4 receptor) or with IL-13Rα1 (forming the type II IL4 receptor).[5]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000077238 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030748 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ McCormick SM, Heller NM (September 2015). "Commentary: IL-4 and IL-13 receptors and signaling". Cytokine. 75 (1): 38–50. doi:10.1016/j.cyto.2015.05.023. PMC 4546937. PMID 26187331.