Interleukin 9

IL9
Identifiers
Aliases	IL9, HP40, IL-9, P40, interleukin 9
External IDs	OMIM: 146931; MGI: 96563; HomoloGene: 492; GeneCards: IL9; OMA:IL9 - orthologs
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q31.1 Start 135,892,246 bp[1] End 135,895,841 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13 B1|13 30.06 cM Start 56,627,090 bp[2] End 56,630,059 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tibial nerve sural nerve amygdala caudate nucleus Brodmann area 9 right frontal lobe substantia nigra primary visual cortex putamen cingulate gyrus Top expressed in embryo entorhinal cortex CA3 field choroid plexus of fourth ventricle zygote inferior colliculi spermatocyte uterus gonad male reproductive system More reference expression data BioGPS More reference expression data
Gene ontology Molecular function interleukin-9 receptor binding cytokine activity growth factor activity cytokine receptor binding Cellular component extracellular region extracellular space Biological process positive regulation of cell growth inflammatory response immune response positive regulation of cell population proliferation regulation of signaling receptor activity interleukin-9-mediated signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3578 16198 Ensembl ENSG00000145839 ENSMUSG00000021538 UniProt P15248 P15247 RefSeq (mRNA) NM_000590 NM_008373 RefSeq (protein) NP_000581 NP_032399 Location (UCSC) Chr 5: 135.89 – 135.9 Mb Chr 13: 56.63 – 56.63 Mb PubMed search [3] [4]
Wikidata
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Interleukin 9, also known as IL-9, is a pleiotropic cytokine (cell signalling molecule) belonging to the group of interleukins.^[5] IL-9 is produced by variety of cells like mast cells, NKT cells, Th2, Th17, Treg, ILC2, and Th9 cells in different amounts. Among them, Th9 cells are regarded as the major CD4+ T cells that produce IL-9.^[6]