Interstate 22

Interstate 22
Corridor X
I-22 highlighted in red
Route information
Maintained by MDOT and ALDOT
Length	202.22 mi[1] (325.44 km)
Existed	2012 (2012)[2]–present
NHS	Entire route
Major junctions
West end	I-269 / US 78 / MS 304 near Byhalia, MS
Major intersections	US 45 in Tupelo, MS SR 4 at the MS/AL Line US 43 / US 278 / SR 171 in Hamilton, AL US 78 / SR 5 in Graysville, AL
East end	I-65 near Birmingham, AL
Location
Country	United States
States	Mississippi, Alabama
Counties	MS: DeSoto, Marshall, Benton, Union, Pontotoc, Lee, Itawamba AL: Marion, Walker, Jefferson
Highway system
Interstate Highway System Main Auxiliary Suffixed Business Future
Mississippi State Highway System Interstate US State
Alabama State Highway System Interstate US State
← MS 21 MS → MS 22 ← SR 21 AL → SR 22

Interstate 22 (I-22) is a 202.22-mile-long (325.44 km) Interstate Highway in the US states of Mississippi and Alabama, connecting I-269 near Byhalia, Mississippi, to I-65 near Birmingham, Alabama. I-22 is also Corridor X of the Appalachian Development Highway System (ADHS). Designated in 2012, I-22 follows the route of older U.S. Route 78 (US 78) and is concurrent with the route for all but its eastern most 11 miles (18 km). The freeway mainly spans rural areas and passes numerous small towns along its route, including Fulton, Tupelo, New Albany, and Holly Springs in Mississippi and Jasper, Winfield, and Hamilton in Alabama.

I-22 was upgraded to Interstate Highway standards to close a gap in the Interstate Highway System, allowing for more direct connections between cities in the southeast with cities in the central part of the country. I-22 indirectly connects I-240, I-40, I-55, and I-69 in the Memphis metropolitan area via US 78 and I-269, and indirectly connects with I-459, I-20, and I-59 in the Birmingham metropolitan area via I-65.