Intradermal injection

Intradermal injection
A medical professional performs an intradermal (ID) injection
MeSHD007271

Intradermal injection (also intracutaneous or intradermic, abbreviated as ID) is a shallow or superficial injection of a substance into the dermis, which is located between the epidermis and the hypodermis. For certain substances, administration via an ID route can result in a faster systemic uptake compared with subcutaneous injections,[1] leading to a stronger immune response to vaccinations, immunology[clarification needed] and novel cancer treatments, and faster drug uptake.[2] Additionally, since administration is closer to the surface of the skin, the body's reaction to substances is more easily visible.[1] However, due to complexity of the procedure compared to subcutaneous injection and intramuscular injection, administration via ID is relatively rare, and is only used for tuberculosis and allergy tests, monkeypox vaccination,[3] and certain therapies.[which?]

  1. ^ a b Taylor CR, Lillis C, LeMone P, Lynn P (2011). Fundamentals of nursing : the art and science of nursing care (7th ed.). Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. pp. 749, 788. ISBN 978-0-7817-9383-4.
  2. ^ Rini CJ, McVey E, Sutter D, Keith S, Kurth HJ, Nosek L, Kapitza C, Rebrin K, Hirsch L, Pettis RJ (August 2015). "Intradermal insulin infusion achieves faster insulin action than subcutaneous infusion for 3-day wear". Drug Delivery and Translational Research. 5 (4): 332–45. doi:10.1007/s13346-015-0239-x. PMC 4529466. PMID 26037035.
  3. ^ "JYNNEOS Vaccine". Centers for Disease Control and Prevention. 2022-10-21. Retrieved 2022-10-23.