Intranasal drug delivery

Intranasal drug delivery occurs when particles are inhaled into the nasal cavity and transported directly into the nervous system. Though pharmaceuticals can be injected into the nose, some concerns include injuries, infection, and safe disposal. Studies demonstrate improved patient compliance with inhalation. Treating brain diseases has been a challenge due to the blood brain barrier. Previous studies evaluated the efficacy of delivery therapeutics through intranasal route for brain diseases and mental health conditions. Intranasal administration is a potential route associated with high drug transfer from nose to brain and drug bioavailability.[1]

  1. ^ Erdő, Franciska; Bors, Luca Anna; Farkas, Dániel; Bajza, Ágnes; Gizurarson, Sveinbjörn (October 2018). "Evaluation of intranasal delivery route of drug administration for brain targeting". Brain Research Bulletin. 143: 155–170. doi:10.1016/j.brainresbull.2018.10.009. hdl:20.500.11815/1402. PMID 30449731. S2CID 53027303.