Intravitreal administration is a route of administration of a drug, or other substance, in which the substance is delivered into the vitreous humor of the eye. "Intravitreal" literally means "inside an eye". Intravitreal injections were first introduced in 1911 when Ohm gave an injection of air into the vitreous humor to repair a detached retina. In the mid-1940s, intravitreal injections became a standard way to administer drugs to treat endophthalmitis and cytomegalovirus retinitis.[1]
- ^ Grzybowski, Andrzej; Told, Reinhard; Sacu, Stefan; Bandello, Francesco; Moisseiev, Elad; Loewenstein, Anat; Schmidt-Erfurth, Ursula (May 2018). "2018 Update on Intravitreal Injections: Euretina Expert Consensus Recommendations". Ophthalmologica. Ophthalmologica 239 (4). 239 (4): 181–193. doi:10.1159/000486145. PMID 29393226. Retrieved 2020-05-02.