| Iontophoresis | |
|---|---|
| ICD-9-CM | 99.27 |
| MedlinePlus | 007293 |
 | This Physics needs attention from an expert in medicine. The specific problem is: The language in this article is difficult for the layperson. Reliability of sources needs checking by experts in these fields. The article could be more informative about the use of this treatment for hyperhidrosis. (December 2018) |
Iontophoresis is a process of transdermal drug delivery by use of a voltage gradient on the skin.[1][2] Molecules are transported across the stratum corneum by electrophoresis and electroosmosis and the electric field can also increase the permeability of the skin.[3][4] These phenomena, directly and indirectly, constitute active transport of matter due to an applied electric current. The transport is measured in units of chemical flux, commonly μmol/(cm2×hour). Iontophoresis has experimental, therapeutic and diagnostic applications.
- ^ Guy, Richard H.; Kalia, Yogeshvar N.; Delgado-Charro, M.Begoña; Merino, Virginia; López, Alicia; Marro, Diego (2000). "Iontophoresis: electrorepulsion and electroosmosis". Journal of Controlled Release. 64 (1–3): 129–132. doi:10.1016/S0168-3659(99)00132-7. ISSN 0168-3659. PMID 10640651.
- ^ Reinauer, S.; Neusser, A.; Schauf, G.; Holzle, E. (1993). "Iontophoresis with alternating current and direct current offset (AC/DC iontophoresis): a new approach for the treatment of hyperhidrosis". British Journal of Dermatology. 129 (2): 166–169. doi:10.1111/j.1365-2133.1993.tb03521.x. ISSN 0007-0963. PMID 7654577. S2CID 9992535.
- ^ Prausnitz, Mark R; Langer, Robert (2008). "Transdermal drug delivery". Nature Biotechnology. 26 (11): 1261–1268. doi:10.1038/nbt.1504. ISSN 1087-0156. PMC 2700785. PMID 18997767.
- ^ Pikal, Michael J. (2001). "The role of electroosmotic flow in transdermal iontophoresis". Advanced Drug Delivery Reviews. 46 (1–3): 281–305. doi:10.1016/S0169-409X(00)00138-1. ISSN 0169-409X. PMID 11259844.