| Iron Regulatory Protein | |||||||
|---|---|---|---|---|---|---|---|
 | |||||||
| Identifiers | |||||||
| Symbol | ACO1 | ||||||
| Alt. symbols | IREB1 | ||||||
| NCBI gene | 48 | ||||||
| HGNC | 117 | ||||||
| OMIM | 100880 | ||||||
| RefSeq | NM_002197 | ||||||
| UniProt | P21399 | ||||||
| Other data | |||||||
| EC number | 4.2.1.3 | ||||||
| Locus | Chr. 9 p21.1 | ||||||
| |||||||
| iron-responsive element-binding protein 2 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | IREB2 | ||||||
| NCBI gene | 3658 | ||||||
| HGNC | 6115 | ||||||
| OMIM | 147582 | ||||||
| RefSeq | NM_004136 | ||||||
| UniProt | P48200 | ||||||
| Other data | |||||||
| Locus | Chr. 15 q25.1 | ||||||
| |||||||
The iron-responsive element-binding proteins, also known as IRE-BP, IRBP, IRP and IFR ,[1] bind to iron-responsive elements (IREs) in the regulation of human iron metabolism.[2]
- ^ Gray, N. K.; Hentze, M. W. (Aug 1994). "Iron regulatory protein prevents binding of the 43S translation pre-initiation complex to ferritin and eALAS mRNAs". EMBO J. 13 (16): 3882–3891. doi:10.1002/j.1460-2075.1994.tb06699.x. PMC 395301. PMID 8070415.
- ^ Eisenstein RS (2000). "Iron regulatory proteins and the molecular control of mammalian iron metabolism". Annu. Rev. Nutr. 20: 627–62. doi:10.1146/annurev.nutr.20.1.627. PMID 10940348.