| Isabella of Aragon | |
|---|---|
| Princess of Asturias | |
 | |
| Queen consort of Portugal | |
| Tenure | 30 September 1497 – 23 August 1498 |
| Born | 2 October 1470 Dueñas, Castile |
| Died | 23 August 1498 (aged 27) Zaragoza, Aragon |
| Burial | Convent of Santa Isabel, Toledo, Castile |
| Spouses | |
| Issue | Miguel de la Paz, Prince of Portugal, Asturias, and Girona |
| House | Trastámara |
| Father | Ferdinand II of Aragon |
| Mother | Isabella I of Castile |
Isabella, Princess of Asturias (2 October 1470 – 23 August 1498) was the eldest daughter and heiress presumptive of King Ferdinand II of Aragon and Queen Isabella I of Castile. She was Queen of Portugal as the wife of King Manuel I from 30 September 1497 until her death the following year.