Isabelle Sprague Smith, also Isabelle Dwight Sprague Smith (November 11, 1861 – December 28, 1950) was an American artist, teacher, and school principal until the mid-1920s. Her students donated the Isabelle D. Sprague Smith Studio to the MacDowell Colony, where she was a member, by 1918. She was director of the People's Institute of New York. Sprague Smith was president of the Bach Festival in New York, and the founder of the Bach Festival in Winter Park, Florida in 1935.